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Literature summary for 3.4.22.55 extracted from

  • Wejda, M.; Impens, F.; Takahashi, N.; Van Damme, P.; Gevaert, K.; Vandenabeele, P.
    Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike (2012), J. Biol. Chem., 287, 33983-33995.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293T cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
eukaryotic translation initiation factor 4B + H2O Homo sapiens Asp563 in eukaryotic translation initiation factor 4B is a caspase-2-preferred cleavage site ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P42575
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
eukaryotic translation initiation factor 4B + H2O Asp563 in eukaryotic translation initiation factor 4B is a caspase-2-preferred cleavage site Homo sapiens ?
-
 ?
N-acetyl-VDVAD-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens N-acetyl-VDVAD + 7-amino-4-methylcoumarin
-
 ?

Synonyms

Synonyms Comment Organism
Casp2
-
 Homo sapiens