Literature summary for 3.4.22.55 extracted from

Jangi, S.M.; Diaz-Perez, J.L.; Ochoa-Lizarralde, B.; Martin-Ruiz, I.; Asumendi, A.; Perez-Yarza, G.; Gardeazabal, J.; Diaz-Ramon, J.L.; Boyano, M.D.
H1 histamine receptor antagonists induce genotoxic and caspase-2-dependent apoptosis in human melanoma cells (2006), Carcinogenesis, 27, 1787-1796.

Search for more literature for 3.4.22.55

Inhibitors

Inhibitors	Comment	Organism	Structure
benzyloxycarbonyl-VDVAD-fluoromethylketone	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
acute T-lymphocytic leukemia cell	treatment of melanoma cells with terfenadine induced DNA damage and caspases 2 activation. A selective inhibitor of caspase-2 (benzyloxycarbonyl-VDVAD-fluoromethylketone) protects melanoma cells from terfenadine-induced apoptosis	Homo sapiens	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)