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Literature summary for 3.4.22.55 extracted from

  • Chang, H.Y.; Yang, X.
    Proteases from cell suicide: functions and regulation of caspases (2000), Microbiol. Mol. Biol. Rev., 64, 821-846.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus phenotype of animals deficient in caspase-2: increased number of oocytes at birth, and oocytes are less susceptible to doxorubicin-induced apoptosis. B cells are partially resistant to death induction by granzyme B, accelerated apoptosis of facial motor neurons ?
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additional information Homo sapiens the enzyme is an apoptosis initiator ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the preferred cleavage sequence is DEHD-/- Homo sapiens ?
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 ?
additional information phenotype of animals deficient in caspase-2: increased number of oocytes at birth, and oocytes are less susceptible to doxorubicin-induced apoptosis. B cells are partially resistant to death induction by granzyme B, accelerated apoptosis of facial motor neurons Mus musculus ?
-
 ?
additional information the enzyme is an apoptosis initiator Homo sapiens ?
-
 ?