Any feedback?
Literature summary for 3.4.22.54 extracted from
- Calpain 3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance (2008), Neuromuscul. Disord., 18, 913-921.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | mutations result in limb girdle muscular dystrophy type 2A | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | not inhibited by calpastatin | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoskeleton | bound to titin | Mus musculus | 5856 | - |
| cytosol | - |
Mus musculus | 5829 | - |
| membrane | - |
Mus musculus | 16020 | - |
| nucleus | - |
Mus musculus | 5634 | - |
| sarcolemma | - |
Mus musculus | 42383 | - |
| soluble | - |
Mus musculus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | submicromolar calcium concentrations necessary | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| skeletal muscle | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| fodrin + H2O | - |
Mus musculus | ? | - |
? | |
| HSP60 + H2O | - |
Mus musculus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | - |
Mus musculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calpain 3 | - |
Mus musculus |
| CAPN3 | - |
Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
