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Literature summary for 3.4.22.53 extracted from

  • Shaikh, S.; Samanta, K.; Kar, P.; Roy, S.; Chakraborti, T.; Chakraborti, S.
    m-Calpain-mediated cleavage of Na+/Ca2+ exchanger-1 in caveolae vesicles isolated from pulmonary artery smooth muscle (2010), Mol. Cell. Biochem., 341, 167-180.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetra(acetoxymethyl) ester
-
Bos taurus
calpeptin
-
Bos taurus
MDL28170
-
Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
vesicle in caveolae vesicles isolated from bovine pulmonary artery smooth muscle plasma membrane Bos taurus 31982
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
1 * 80000 + 1 * 28000, SDS-PAGE Bos taurus
80000
-
1 * 80000 + 1 * 28000, SDS-PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pulmonary artery smooth muscle cell
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Na+/Ca2+ exchanger-1 + H2O calcium-dependent proteolytic cleavage of Na+/Ca2+ exchanger-1 occurs in the caveolae vesicles Bos taurus 82 kDa fragment + ?
-
?

Subunits

Subunits Comment Organism
heterodimer 1 * 80000 + 1 * 28000, SDS-PAGE Bos taurus

Synonyms

Synonyms Comment Organism
m-calpain
-
Bos taurus