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Literature summary for 3.4.22.53 extracted from
- Actin-binding protein-1 interacts with WASp-interacting protein to regulate growth factor-induced dorsal ruffle formation (2010), Mol. Biol. Cell, 21, 186-197.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cortactin + H2O | Rattus norvegicus | - |
? | - |
? |  |
| mammalian actin-binding protein-1 + H2O | Rattus norvegicus | the preferred cleavage site occurs between the actin-binding domain and the proline-rich region, generating a C-terminal mAbp1 fragment | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cortactin + H2O | - |
Rattus norvegicus | ? | - |
? | |
| mammalian actin-binding protein-1 + H2O | the preferred cleavage site occurs between the actin-binding domain and the proline-rich region, generating a C-terminal mAbp1 fragment | Rattus norvegicus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calpain 2 | - |
Rattus norvegicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | calpain 2 proteolysis of mAbp1 negatively regulates dorsal ruffle formation | Rattus norvegicus |
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Release 2023.1 (January 2023)
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