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Literature summary for 3.4.22.53 extracted from

  • Ma, H.; Tochigi, A.; Shearer, T.R.; Azuma, M.
    Calpain inhibitor SNJ-1945 attenuates events prior to angiogenesis in cultured human retinal endothelial cells (2009), J. Ocul. Pharmacol. Ther., 25, 409-414.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.53

Inhibitors

Inhibitors Comment Organism Structure
SNJ-1945
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
retinal microvascular endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-spectrin + H2O
-
 Homo sapiens ?
-
 ?
casein + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
calpain 2
-
 Homo sapiens
EC 3.4.22.17 formerly Homo sapiens
m-calpain
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens incubation of human retinal microvascular endothelial cells with vascular endothelial growth factor results in 1.6fold increased activity of calpain 2 at 24 h up