Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpastatin | endogenous inhibitor | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | calpain 2 is activated with addition of CaCl+ to 1 mM | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
androgen receptor + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
CWR22-Rv1 cell | - |
Homo sapiens | - |
DU-145 cell | - |
Homo sapiens | - |
LNCaP cell | - |
Homo sapiens | - |
PC-3 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
androgen receptor + H2O | - |
Homo sapiens | ? | - |
? | |
androgen receptor + H2O | - |
Homo sapiens | low molecular weight androgen receptor + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calpain 2 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | a 6-day treatment with siRNA results in an about 60% reduction of calpain 2 protein levels in R1 cells | down |
General Information | Comment | Organism |
---|---|---|
physiological function | calpain 2 plays a role in the generation of the low molecular weight-androgen receptor in CWR22-R1 cells | Homo sapiens |