Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.53 extracted from

  • Babbin, B.A.; Koch, S.; Bachar, M.; Conti, M.A.; Parkos, C.A.; Adelstein, R.S.; Nusrat, A.; Ivanov, A.I.
    Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion (2009), Am. J. Pathol., 174, 436-448.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
acetyl-Leu-Leu-Nle-CHO complete inhibition at 0.001 mM Homo sapiens
calpeptin complete inhibition at 0.001 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic epithelial cell
-
Homo sapiens
-
SK-CO15 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
casein + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
calpain 2
-
Homo sapiens
m-calpain
-
Homo sapiens

General Information

General Information Comment Organism
malfunction calpain inhibition blocks the increased colonic epithelial cell invasion caused by NM IIA knockdown Homo sapiens