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Literature summary for 3.4.22.53 extracted from

  • Sanchez-Sanchez, F.; Martinez-Redondo, F.; Aroca-Aguilar, J.D.; Coca-Prados, M.; Escribano, J.
    Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease (2007), J. Biol. Chem., 282, 27810-27824.
    View publication on PubMed
Search for more literature for 3.4.22.53

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
myocillin + H2O Homo sapiens calpain II is responsible for the intracellular processing of myocilin in the lumen of the endoplasmic reticulum. It is proposed that this cleavage might regulate extracellular interactions of myocilin, contributing to the control of intraocular pressure ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myocillin + H2O
-
 Homo sapiens ?
-
 ?
myocillin + H2O calpain II is responsible for the intracellular processing of myocilin in the lumen of the endoplasmic reticulum. It is proposed that this cleavage might regulate extracellular interactions of myocilin, contributing to the control of intraocular pressure Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
calpain II
-
 Homo sapiens