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Literature summary for 3.4.22.52 extracted from

  • Stifanese, R.; Averna, M.; De Tullio, R.; Pedrazzi, M.; Milanese, M.; Bonifacino, T.; Bonanno, G.; Salamino, F.; Pontremoli, S.; Melloni, E.
    Role of calpain-1 in the early phase of experimental ALS (2014), Arch. Biochem. Biophys., 562, 1-8.
    View publication on PubMed
Search for more literature for 3.4.22.52

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-spectrin II + H2O Mus musculus
-
 ?
-
 ?
neuronal nitric oxide synthase + H2O Mus musculus
-
 ?
-
 ?
NR2B subunit of NMDA receptor + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
spinal cord
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-spectrin II + H2O
-
 Mus musculus ?
-
 ?
neuronal nitric oxide synthase + H2O
-
 Mus musculus ?
-
 ?
NR2B subunit of NMDA receptor + H2O
-
 Mus musculus ?
-
 ?

Expression

Organism Comment Expression
Mus musculus an increase in the activity of calpain-1 takes place at an early stage of amyotrophic lateral sclerosis up

General Information

General Information Comment Organism
physiological function the enzyme plays a role in the early phase and during progression of amyotrophic lateral sclerosis Mus musculus