Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpastatin | - |
Rattus norvegicus | |
MDL-28170 | Cbz-Val-Phel-alanial | Rattus norvegicus | |
PD150606 | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | a pool of micro-calpain is localized to the mitochondrial intermembrane space | Rattus norvegicus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | incubation with 5 mM Ca2+ results in the activation of micro-calpain | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
apoptosis-inducing factor + H2O | Rattus norvegicus | mitochondrial micro-calpain is the protease responsible for processing apoptosis-inducing factor prior to its release | truncated apoptosis-inducing factor + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
apoptosis-inducing factor + H2O | mitochondrial micro-calpain is the protease responsible for processing apoptosis-inducing factor prior to its release | Rattus norvegicus | truncated apoptosis-inducing factor + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calpain 1 | - |
Rattus norvegicus |
micro-calpain | - |
Rattus norvegicus |