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Literature summary for 3.4.22.49 extracted from

  • Kumar, R.
    Separase Function beyond cohesion cleavage and an emerging oncogene (2017), J. Cell. Biochem., 118, 1283-1299 .
    View publication on PubMed
Search for more literature for 3.4.22.49

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana A0A1P8B3N4
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Caenorhabditis elegans
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Drosophila melanogaster Q9VRN6
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Picea abies R4XPW1
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Saccharomyces cerevisiae Q03018
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Schizosaccharomyces pombe P18296
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Schizosaccharomyces pombe ATCC 24843 P18296
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Synonyms

Synonyms Comment Organism
AtESP
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 Arabidopsis thaliana
Cut1
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 Schizosaccharomyces pombe
Esp1
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 Saccharomyces cerevisiae
sep-1
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 Caenorhabditis elegans
SSE
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 Drosophila melanogaster

General Information

General Information Comment Organism
physiological function chiasmata resolution and segregation of homologous chromosome pair. Role in DNA repair. Assembly and elongation of spindle at mitotic anaphase. Spindle formation in meiosis. Karyokinesis (division of nucleus). Spindle midzone assembly. Apoptosis promotion. Cleavage of Slk19. Cdc14 activation and release of Cdc14 from nucleolus Saccharomyces cerevisiae
physiological function involved in proper positioning of the centrosomes during the first asymmetric mitotic division, in the development of egg shell and in membrane trafficking Caenorhabditis elegans
physiological function role in DNA repair. Involved in positioning of spindle pole body Schizosaccharomyces pombe
physiological function the enzyme is involved in cell expansion Picea abies
physiological function the enzyme is involved in establishment of cell polarity and cytokinesis, in microtubule polymerization and Kin7 activation Arabidopsis thaliana
physiological function the enzyme is involved in reorganization and dynamics in epithelial cells, in telomere capping and in inactivation of alternative conjunction at anaphase I onset Drosophila melanogaster