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Literature summary for 3.4.22.49 extracted from
- Separase-mediated cleavage of cohesin at interphase is required for DNA repair (2004), Nature, 430, 1044-1048.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cohesin + H2O | Schizosaccharomyces pombe | separase-mediated cleavage of cohesin at interphase is required for DNA repair. It is proposed that the securin-separase complex might aid DNA repair by removing local cohesin in interphase cells | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Schizosaccharomyces pombe | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cohesin + H2O | separase-mediated cleavage of cohesin at interphase is required for DNA repair. It is proposed that the securin-separase complex might aid DNA repair by removing local cohesin in interphase cells | Schizosaccharomyces pombe | ? | - |
? | |
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