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Literature summary for 3.4.22.49 extracted from

  • Pandey, R.; Heidmann, S.; Lehner, C.F.
    Epithelial re-organization and dynamics of progression through mitosis in Drosophila separase complex mutants (2005), J. Cell Sci., 118, 733-742.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Drosophila sp. (in: flies) separase is primarily required for sister chromatid separation during mitotic and meiotic division, by cleavage of a subunit of the cohesin complex. Separase is also and perhaps indirectly important for epithelial integrity ?
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Organism

Organism UniProt Comment Textmining
Drosophila sp. (in: flies)
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Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information separase is primarily required for sister chromatid separation during mitotic and meiotic division, by cleavage of a subunit of the cohesin complex. Separase is also and perhaps indirectly important for epithelial integrity Drosophila sp. (in: flies) ?
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