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Literature summary for 3.4.22.43 extracted from

  • Sevenich, L.; Hagemann, S.; Stoeckle, C.; Tolosa, E.; Peters, C.; Reinheckel, T.
    Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice (2010), Biochimie, 92, 1674-1680.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in thymus of transgenic Mus musculus Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Elastin + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
thymic cortex in the human thymic cortex, CTSV is the predominately expressed protease Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Elastin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
cathepsin L2
-
 Homo sapiens
CTSV
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function expression of CTSV rescues the reduced frequency of CD4+ T cells in cysteine protease cathepsin L-deficient mice with H-2b haplotype Homo sapiens