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Literature summary for 3.4.22.40 extracted from

  • Kajiya, A.; Kaji, H.; Isobe, T.; Takeda, A.
    Processing of amyloid beta-peptides by neutral cysteine protease bleomycin hydrolase (2006), Protein Pept. Lett., 13, 119-123.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
x * 48000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
2-days-old Sprague-Dawley rats
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme from epidermis of newborn rats Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
epidermis of newborn rats Rattus norvegicus
-
skin
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid peptide Abeta1-40 + H2O processing by cleavage at bonds His14-Gln15 and Phe19-Phe20, endopeptidase activity, substrate preparation, overview Rattus norvegicus peptide fragments product determination by MALDI-TOF mass spectrometry ?
amyloid peptide Abeta1-42 + H2O processing by cleavage at bonds His14-Gln15 and Phe19-Phe20, endopeptidase activity, substrate preparation, overview Rattus norvegicus peptide fragments product determination by MALDI-TOF mass spectrometry ?
amyloid peptide Abeta3-42 + H2O processing Rattus norvegicus ?
-
?
additional information the enzyme is a neutral cysteine protease, processing specificity on amyloid bet-peptides depends on the substrate structure and sequence, overview Rattus norvegicus ?
-
?

Subunits

Subunits Comment Organism
? x * 48000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
BH
-
Rattus norvegicus