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Literature summary for 3.4.22.39 extracted from
- Activation of the adenovirus protease requires sequence elements from both ends of the activating peptide (1996), J. Biol. Chem., 271, 32511-32514.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | unidentified adenovirus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| unidentified adenovirus | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| Cleaves proteins of the adenovirus and its host cell at two consensus sites: -Yaa-Xaa-Gly-Gly-/-Xaa- and -Yaa-Xaa-Gly-Xaa-/-Gly- (in which Yaa is Met, Ile or Leu, and Xaa is any amino acid) | consensus sequences | unidentified adenovirus | |
| Cleaves proteins of the adenovirus and its host cell at two consensus sites: -Yaa-Xaa-Gly-Gly-/-Xaa- and -Yaa-Xaa-Gly-Xaa-/-Gly- (in which Yaa is Met, Ile or Leu, and Xaa is any amino acid) | the GXG consensus site is cleaved more rapidly than the GGX site | unidentified adenovirus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Ly-AnLRGA-GFSWK-ctmr-R | - |
unidentified adenovirus | ? | - |
? |  |
| Ly-AnLRGG-AFSWK-ctmr-R | - |
unidentified adenovirus | ? | - |
? | |
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