Application | Comment | Organism |
---|---|---|
medicine | cathepsin K inhibitors may aid in the management of canine osteosarcoma-related malignant osteolysis | Canis lupus familiaris |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasmic vesicle | - |
Canis lupus familiaris | 31410 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37000 | - |
x * 37000, inactive propeptide, SDS-PAGE | Canis lupus familiaris |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen type I + H2O | Canis lupus familiaris | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Abrams cell | - |
Canis lupus familiaris | - |
COS-31 cell | - |
Canis lupus familiaris | - |
D17 cell | - |
Canis lupus familiaris | - |
HMPOS cell | - |
Canis lupus familiaris | - |
osteoclast | - |
Canis lupus familiaris | - |
osteosarcoma cell | - |
Canis lupus familiaris | - |
POS cell | - |
Canis lupus familiaris | - |
serum | - |
Canis lupus familiaris | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen type I + H2O | - |
Canis lupus familiaris | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 37000, inactive propeptide, SDS-PAGE | Canis lupus familiaris |
Synonyms | Comment | Organism |
---|---|---|
catK | - |
Canis lupus familiaris |
Organism | Comment | Expression |
---|---|---|
Canis lupus familiaris | in osteosarcoma cells, tissue growth factor beta1 induces the secretion of cathepsin K by about 3fold | up |