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Literature summary for 3.4.22.38 extracted from

  • Bai, L.; Beckers, L.; Wijnands, E.; Lutgens, S.P.; Herias, M.V.; Saftig, P.; Daemen, M.J.; Cleutjens, K.; Lutgens, E.; Biessen, E.A.; Heeneman, S.
    Cathepsin K gene disruption does not affect murine aneurysm formation (2010), Atherosclerosis, 209, 96-103.
    View publication on PubMed
Search for more literature for 3.4.22.38

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Mus musculus 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
collagen I + H2O Mus musculus
-
 ?
-
 ?
Collagen IV + H2O Mus musculus
-
 ?
-
 ?
Elastin + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
abdominal aorta
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen I + H2O
-
 Mus musculus ?
-
 ?
Collagen IV + H2O
-
 Mus musculus ?
-
 ?
Elastin + H2O
-
 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
catK
-
 Mus musculus

General Information

General Information Comment Organism
malfunction catK deficiency has major impact on various vasculopathies, catK deficiency does not protect against aneurysm formation nor does it affect medial elastin breaks, cathepsin K deficiency with angiotensin II infusion increases granulocyte population and activates T cell numbers Mus musculus