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Literature summary for 3.4.22.37 extracted from
- Sequential action of R- and K-specific gingipains of Porphyromonas gingivalis in the generation of the haem-containing pigment from oxyhemoglobin (2007), Arch. Biochem. Biophys., 465, 44-49.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| leupeptin | - |
Porphyromonas gingivalis |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| oxyhaemoglobin + H2O | Porphyromonas gingivalis | data indicate direct product formation without the occurrence of intermediates, reaction required for the formation the the my-oxo heam dimer containing black pigment | methaemoglobin | - |
? | |
| oxyhaemoglobin + H2O | Porphyromonas gingivalis HG66 | data indicate direct product formation without the occurrence of intermediates, reaction required for the formation the the my-oxo heam dimer containing black pigment | methaemoglobin | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Porphyromonas gingivalis | - |
- |
- |
| Porphyromonas gingivalis HG66 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Porphyromonas gingivalis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| oxyhaemoglobin + H2O | data indicate direct product formation without the occurrence of intermediates, reaction required for the formation the the my-oxo heam dimer containing black pigment | Porphyromonas gingivalis | methaemoglobin | - |
? | |
| oxyhaemoglobin + H2O | data indicate direct product formation without the occurrence of intermediates, reaction required for the formation the the my-oxo heam dimer containing black pigment | Porphyromonas gingivalis HG66 | methaemoglobin | - |
? | |
| oxyhaemoglobin + H2O | data indicate direct product formation without the occurrence of intermediates | Porphyromonas gingivalis | methaemoglobin + ? | - |
? | |
| oxyhaemoglobin + H2O | data indicate direct product formation without the occurrence of intermediates | Porphyromonas gingivalis HG66 | methaemoglobin + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Arg-gingipain | - |
Porphyromonas gingivalis |
| HRgpA | - |
Porphyromonas gingivalis |
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Release 2023.1 (January 2023)
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