Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.36 extracted from

  • White, J.; Beckford, J.; Yadegarynia, S.; Ngo, N.; Lialiutska, T.; DAlarcao, M.
    Some natural flavonoids are competitive inhibitors of caspase-1, -3, and -7 despite their cellular toxicity (2012), Food Chem., 131, 1453-1459.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.36

Inhibitors

Inhibitors Comment Organism Structure
kaempferol
-
 Homo sapiens
luteolin
-
 Homo sapiens
myricetin
-
 Homo sapiens
quercetin
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MDA-MB-231 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ac-LEHD-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens Ac-LEHD + 7-amino-4-methylcoumarin
-
 ?

Synonyms

Synonyms Comment Organism
caspase-1
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.014
-
 myricetin pH not specified in the publication, 30°C Homo sapiens
0.118
-
 luteolin pH not specified in the publication, 30°C Homo sapiens
0.3
-
 quercetin pH not specified in the publication, 30°C, value above Homo sapiens
0.3
-
 kaempferol pH not specified in the publication, 30°C, value above Homo sapiens