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Literature summary for 3.4.22.36 extracted from

  • Guma, M.; Ronacher, L.; Liu-Bryan, R.; Takai, S.; Karin, M.; Corr, M.
    Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation (2009), Arthritis Rheum., 60, 3642-3650.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.36

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pro-interleukin-1beta + H2O Mus musculus
-
 mature interleukin-1beta + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell
-
 Mus musculus
-
neutrophil
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pro-interleukin-1beta + H2O
-
 Mus musculus mature interleukin-1beta + ?
-
 ?

Synonyms

Synonyms Comment Organism
ICE
-
 Mus musculus
IL-1betaΒ–-converting enzyme
-
 Mus musculus

General Information

General Information Comment Organism
physiological function the production of interleukin-1beta by neutrophils and mast cells is not exclusively dependent on caspase 1, and other proteases can compensate for the loss of caspase 1 in vivo Mus musculus