Literature summary for 3.4.22.34 extracted from

Zhao, T.; Li, Z.; Guo, Z.; Wang, A.; Liu, Z.; Zhao, Q.; Li, Y.; McKenzie, E.A.; Diao, A.
Functional recombinant human Legumain protein expression in Pichia pastoris to enable screening for Legumain small molecule inhibitors (2018), Protein Expr. Purif., 150, 12-16 .

Search for more literature for 3.4.22.34

Cloned(Commentary)

Cloned (Comment)	Organism
Pichia pastoris expression system can produce highly active recombinant legumain protein allowing it to be used for high-throughput screening applications	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
terramycin	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
lysosome	-	Homo sapiens	5764	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q99538	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	the optimum pH for the autocatalytic activation of recombinant legumain is very acidic at a pH value of 3	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzyloxycarbonyl-Ala-Ala-Asn-7-amido-4-methylcoumarin + H2O	-	Homo sapiens	benzyloxycarbonyl-Ala-Ala-Asn + 7-amino-4-methylcoumarin	-	?

Synonyms

Synonyms	Comment	Organism
LGMN	-	Homo sapiens

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Release 2023.1 (January 2023)