Any feedback?
Literature summary for 3.4.22.34 extracted from
- On Blastocystis secreted cysteine proteases a legumain-activated cathepsin B increases paracellular permeability of intestinal Caco-2 cell monolayers (2016), Parasitology, 143, 1713-1722 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Blastocystis hominis |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 40000 | - |
SDS-PAGE | Blastocystis hominis |
| 45200 | - |
calculated | Blastocystis hominis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Blastocystis hominis | D8M176 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | activation of the recombinant legumain is autocatalytic and triggered by acidic pH | Blastocystis hominis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-Ala-Ala-Asn-7-amido-4-methylcoumarin + H2O | - |
Blastocystis hominis | benzyloxycarbonyl-Ala-Ala-Asn + 7-amino-4-methylcoumarin | - |
? |  |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 3 | 4 | - |
Blastocystis hominis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
