Application | Comment | Organism |
---|---|---|
medicine | bromelain has gained wide acceptance and compliance as a phytotherapeutical drug. Cysteine proteases in pineapple (Ananas comosus) plants are phytotherapeutical agents that demonstrate antiedematous, anti-inflammatory, anti-thrombotic and fibrinolytic activities | Ananas comosus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ananas comosus | O23791 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fruit | - |
Ananas comosus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzyl-Phe-Val-Arg-4-nitroanilide + H2O | preferred substrate of fruit bromelain | Ananas comosus | benzyl-Phe-Val-Arg + 4-nitroaniline | - |
? | |
benzyloxycarbonyl-Arg-Arg-4-nitroanilide + H2O | - |
Ananas comosus | benzyloxycarbonyl-Arg-Arg + 4-nitroaniline | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 25000-31000, fruit bromelain, SDS-PAGE | Ananas comosus |
More | comparative structural analysis of fruit and stem bromelain from Ananas comosus | Ananas comosus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Ananas comosus | isoelectric focusing | - |
4.6 |
General Information | Comment | Organism |
---|---|---|
additional information | comparative structural analysis of fruit and stem bromelain from Ananas comosus, structure homology modelling, model domain organisation, overview. The proteolytic fraction of pineapple stem is termed stem bromelain, while the one presents in the fruit is known as fruit bromelain (EC 3.4.22.33). NCBI conserved domain analysis reveals two domains of fruit and stem bromelain: cathepsin propeptide inhibitor (I29) and peptidase C1 | Ananas comosus |