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Literature summary for 3.4.22.29 extracted from

  • Alvarez, E.; Castello, A.; Carrasco, L.; Izquierdo, J.
    Poliovirus 2A protease triggers a selective nucleo-cytoplasmic redistribution of splicing factors to regulate alternative pre-mRNA splicing (2013), PLoS ONE, 8, e73723.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Huh7-T7 cells Enterovirus C

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
16000
-
x * 16000, SDS-PAGE Enterovirus C

Organism

Organism UniProt Comment Textmining
Enterovirus C
-
-
-

Subunits

Subunits Comment Organism
? x * 16000, SDS-PAGE Enterovirus C

Synonyms

Synonyms Comment Organism
2A protease
-
Enterovirus C
2Apro
-
Enterovirus C

General Information

General Information Comment Organism
physiological function expression of 2A protease induces a selective nucleo-cytoplasm translocation of several important RNA binding proteins and splicing factors. The enzyme can target alternative pre-mRNA splicing by regulating protein shuttling between the nucleus and the cytoplasm. The enzyme regulates alternative splicing of the Fas exon 6 Enterovirus C