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Literature summary for 3.4.22.29 extracted from

  • Wang, C.L.; Wang, J.Y.; Liu, Z.Y.; Ma, X.M.; Wang, X.W.; Jin, H.; Zhang, X.P.; Fu, D.; Hou, L.J.; Lu, Y.C.
    Ubiquitin-specific protease 2a stabilizes MDM4 and facilitates the p53-mediated intrinsic apoptotic pathway in glioblastoma (2014), Carcinogenesis, 35, 1500-1509.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
mouse double minute 2 + H2O
-
Homo sapiens ?
-
?
mouse double minute 4 + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ubiquitin-specific protease 2a
-
Homo sapiens
USP2a
-
Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme binds to and stabilizes mouse double minute 4, thus in turn, it enhances the mitochondrial localization of p53 and promotes apoptosis in glioma cells Homo sapiens