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Literature summary for 3.4.22.29 extracted from

  • Seipelt, J.; Liebig, H.D.; Sommergruber, W.; Gerner, C.; Kuechler, E.
    2A proteinase of human rhinovirus cleaves cytokeratin 8 in infected HeLa cells (2000), J. Biol. Chem., 275, 20084-20089.
    View publication on PubMed
Search for more literature for 3.4.22.29

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cytokeratin 8 + H2O coxsackievirus
-
 ?
-
 ?
cytokeratin 8 + H2O Human rhinovirus sp. the cleavage results in removal of 14 amino acids from the N-terminal head domain of cytokeratin 8. Cleavage occurs late in the infection cycle at the time of the onset of the cytopathic effect ?
-
 ?

Organism

Organism UniProt Comment Textmining
coxsackievirus
-
-
-
Human rhinovirus sp.
-
 serotypes 2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cytokeratin 8 + H2O
-
 coxsackievirus ?
-
 ?
cytokeratin 8 + H2O the cleavage results in removal of 14 amino acids from the N-terminal head domain of cytokeratin 8 Human rhinovirus sp. ?
-
 ?
cytokeratin 8 + H2O the cleavage results in removal of 14 amino acids from the N-terminal head domain of cytokeratin 8. Cleavage occurs late in the infection cycle at the time of the onset of the cytopathic effect Human rhinovirus sp. ?
-
 ?
KSYKVSTSGPRAFSSR + H2O
-
 coxsackievirus KSYKVSTS + GPRAFSSR
-
 ?
KSYKVSTSGPRAFSSR + H2O
-
 Human rhinovirus sp. KSYKVSTS + GPRAFSSR
-
 ?