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Literature summary for 3.4.22.29 extracted from
- The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis (1999), EMBO J., 18, 5463-5475.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| crystals grown at 4°C by hanging drop vapour diffusion method | Human rhinovirus sp. |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | a tightly bound Zn2+ is essential for stability of the enzyme, is tetrahedrally coordinated by three cysteine sulfurs and one histidine nitrogen | Human rhinovirus sp. |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human rhinovirus sp. | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the active site of the enzyme consists of a catalytic triad formed by His18, Asp35 and Cys106 | Human rhinovirus sp. | ? | - |
? | |
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Release 2023.1 (January 2023)
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