Literature summary for 3.4.22.28 extracted from

Gouvea, I.E.; Santos, J.A.; Burlandy, F.M.; Tersariol, I.L.; da Silva, E.E.; Juliano, M.A.; Juliano, L.; Cunha, R.L.
Poliovirus 3C proteinase inhibition by organotelluranes (2011), Biol. Chem., 392, 587-591.

Search for more literature for 3.4.22.28

Inhibitors

Inhibitors	Comment	Organism	Structure
ammonium trichloro (dioxoethylene-O,O')tellurate	-	Human poliovirus 3
bis-vinylic organotellurane	-	Human poliovirus 3
chloro-telluroxetane	-	Human poliovirus 3

Organism

Organism	UniProt	Comment	Textmining
Human poliovirus 3	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Abz-EALFQGPLQ-EDDnp + H2O	-	Human poliovirus 3	Abz-EALFQ + GPLQ-EDDnp	-	?

Synonyms

Synonyms	Comment	Organism
3C protease	-	Human poliovirus 3

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
25	-	assay at	Human poliovirus 3

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0001	-	25°C, pH not specified in the publication	Human poliovirus 3	bis-vinylic organotellurane
0.00084	-	25°C, pH not specified in the publication	Human poliovirus 3	chloro-telluroxetane
0.03	-	25°C, pH not specified in the publication, value above	Human poliovirus 3	ammonium trichloro (dioxoethylene-O,O')tellurate

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Release 2023.1 (January 2023)