Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | activation, 4 mM | Rattus norvegicus | |
cysteine | activation, 4 mM | Rattus norvegicus | |
DTT | activation, 2 mM | Rattus norvegicus | |
EDTA | activation | Rattus norvegicus | |
EDTA | 2 mM | Rattus norvegicus | |
GSH | activation, 4 mM | Rattus norvegicus | |
sulfhydryl compounds | activation | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4,4'-dipyridyl disulfide | - |
Rattus norvegicus | |
antipain | - |
Rattus norvegicus | |
iodoacetamide | - |
Rattus norvegicus | |
iodoacetate | - |
Rattus norvegicus | |
leupeptin | - |
Rattus norvegicus | |
additional information | no inhibition by native ribonuclease A | Rattus norvegicus | |
N-ethylmaleimide | - |
Rattus norvegicus | |
Oxidized ribonuclease A | tyrosine aminotransferase as substrate | Rattus norvegicus | |
PCMB | - |
Rattus norvegicus | |
PMSF | - |
Rattus norvegicus | |
tosyl-L-lysine chloromethyl ketone | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Rattus norvegicus | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
albino male Holtzman rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Acid-denatured hemoglobin + H2O | - |
Rattus norvegicus | ? | - |
? | |
azocasein + H2O | - |
Rattus norvegicus | ? | - |
? | |
additional information | no hydrolysis of synthetic low MW substrates for exopeptidases, e.g. Gly-(L)-Phe-beta-naphthylamide, L-Ser-(L)-Tyr-beta-naphthylamide, L-Leu-beta-naphthylamide, L-Arg-beta-naphthylamide, L-leucinamide, hippuryl-L-arginine, hippuryl-L-phenylalanine, N-benzoyl-L-tyrosine ethyl ester | Rattus norvegicus | ? | - |
? | |
additional information | little or no activity at 0øC with glucose 6-phosphate dehydrogenase, native ribonuclease A, native bovine serum albumin, cytochrome c or oxidized insulin B-chain | Rattus norvegicus | ? | - |
? | |
Performic acid-oxidized ribonuclease A + H2O | even at 0øC | Rattus norvegicus | Hydrolyzed performic acid-oxidized ribonuclease A | several fragments | ? | |
Tyrosine aminotransferase form I + H2O | thereby generating multiple forms of tyrosine aminotransferase | Rattus norvegicus | Tyrosine aminotransferase form II and III + acidic peptide of MW 4500 peptide | enzyme form III: dimer of MW 49000 | ? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
- |
- |
assay at, tyrosine aminotransferase as substrate | Rattus norvegicus |
37 | - |
assay at, proteins as substrate | Rattus norvegicus |