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Literature summary for 3.4.22.2 extracted from

  • Achilles, K.; Schirmeister, T.; Otto, H.H.
    beta-Lactam derivatives as enzyme inhibitors: 1-peptidyl derivatives of 4-phenylazetidin-2-one as inhibitors of elastase and papain (2000), Arch. Pharm., 333, 243-253.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(2-[(S,R)-2-oxo-4-phenylazetidin-1-yl]acetyl)-L-phenylalanine methyl ester weak inhibitor, irreversible Carica papaya
(2-[(S,R)-2-oxo-4-phenylazetidin-1-yl]acetyl)-L-Val benzyl ester weak inhibitor, irreversible Carica papaya
(S,R)-1-[(S)-N-(tert-butyloxycarbonyl)alanyl]-4-phenylazetidin-2-one weak inhibitor, irreversible Carica papaya
ethyl-(RS)-2-(2-oxo-4-phenylazetidin-1-yl)acetate weak inhibitor, irreversible Carica papaya

Organism

Organism UniProt Comment Textmining
Carica papaya
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
latex
-
Carica papaya
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-Ala-Ala-Ala-p-nitroanilide + H2O
-
Carica papaya ?
-
?