Cloned (Comment) | Organism |
---|---|
expressed in Pichia pastoris | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
in complex with inhibitor Phe-Tyr-(OBut)-COCHO, hanging drop vapor diffusion method, using 15% (w/v) PEG 8K and 200 mM ammonium sulfate, pH 4.8. In complex with inhibitor Phe-Tyr-(tert-Bu)-diazomethylketone, hanging drop vapor diffusion method, using 30% (w/v) PEG 8K and 200 mM ammonium sulfate, pH 5.2 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Phe-Tyr-(OBut)-COCHO | potent, reversible, synthetic peptidyl inhibitor of cathepsin L | Homo sapiens | |
Phe-Tyr-(tert-Bu)-diazomethylketone | irreversible inhibitor that can inactivate cathepsin L at micromolar concentrations | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P07711 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
CatL | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000006 | - |
Phe-Tyr-(OBut)-COCHO | pH and temperature not specified in the publication | Homo sapiens |