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Literature summary for 3.4.22.15 extracted from

  • Rodrigues, A.C.; Garcia, H.A.; Ortiz, P.A.; Cortez, A.P.; Martinkovic, F.; Paiva, F.; Batista, J.S.; Minervino, A.H.; Campaner, M.; Pral, E.M.; Alfieri, S.C.; Teixeira, M.M.
    Cysteine proteases of Trypanosoma (Megatrypanum) theileri: Cathepsin L-like gene sequences as targets for phylogenetic analysis, genotyping diagnosis (2010), Parasitol. Int., 59, 318-325.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
dithiothreitol stimulates at 2 mM Trypanosoma theileri

Application

Application Comment Organism
additional information CATL gene sequences are useful for diagnosis, population genotyping and evolutionary studies of Trypanosoma theileri Trypanosoma theileri

Inhibitors

Inhibitors Comment Organism Structure
E-64 99.7% inhibition at 0.01 mM Trypanosoma theileri

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Trypanosoma theileri
-
?
-
?

Organism

Organism UniProt Comment Textmining
Trypanosoma theileri E5DHH4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Trypanosoma theileri ?
-
?
Nalpha-benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
-
Trypanosoma theileri Nalpha-benzyloxycarbonyl-L-Phe-L-Arg + 7-amino-4-methylcoumarin
-
?

Synonyms

Synonyms Comment Organism
cathepsin L-like
-
Trypanosoma theileri
CatL
-
Trypanosoma theileri

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
-
Trypanosoma theileri