Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli, the zymogen proSCP is secreted to the Escherichia coli periplasm followed by subsequent cleavage of the signal peptide | Streptococcus pyogenes |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.193 | - |
benzyloxycarbonyl-Val-Arg-4-methylcoumarinyl-7-amide | - |
Streptococcus pyogenes |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pyogenes | - |
- |
- |
Streptococcus pyogenes B220 | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | autocatalytic maturation of the zymogen proceeds through the sequential appearance of at least six intermediates, resulting from cleavage after Lys26, Asn41, Lys101, Ala112 and Lys118 | Streptococcus pyogenes |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-aminobenzoyl-Ala-Ala-Ile-Lys-Ala-Gly-Ala-Arg + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
3-aminobenzoyl-Ala-Ala-Ile-Lys-Ala-Gly-Ala-Arg + H2O | - |
Streptococcus pyogenes B220 | ? | - |
? | |
3-aminobenzoyl-Ala-Glu-Ile-Lys-Gln-Pro-Val-Val + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
3-aminobenzoyl-Asp-Lys-Val-Asn-Leu-Gly-Gly-Glu + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
3-aminobenzoyl-Asp-Lys-Val-Asn-Leu-Gly-Gly-Glu + H2O | - |
Streptococcus pyogenes B220 | ? | - |
? | |
3-aminobenzoyl-Glu-Gln-Ile-Lys-Glu-Asn-Lys-Lys + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
3-aminobenzoyl-Glu-Gln-Ile-Lys-Glu-Asn-Lys-Lys + H2O | - |
Streptococcus pyogenes B220 | ? | - |
? | |
3-aminobenzoyl-Thr-Thr-Thr-Ala-Gly-Thr-Ala-Glu + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
3-aminobenzoyl-Thr-Thr-Thr-Ala-Gly-Thr-Ala-Glu + H2O | - |
Streptococcus pyogenes B220 | ? | - |
? | |
benzyloxycarbonyl-Val-Arg-4-methylcoumarinyl-7-amide + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
benzyloxycarbonyl-Val-Arg-4-methylcoumarinyl-7-amide + H2O | - |
Streptococcus pyogenes B220 | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.042 | - |
benzyloxycarbonyl-Val-Arg-4-methylcoumarinyl-7-amide | - |
Streptococcus pyogenes |