Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
28000 | - |
x * 28000, mature enzyme | Streptococcus pyogenes |
40000 | - |
x * 40000, proenzyme, estimated from amino acid sequence | Streptococcus pyogenes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha1-antitrypsin + H2O | Streptococcus pyogenes | - |
? | - |
? | |
C5a peptidase + H2O | Streptococcus pyogenes | cleavage sites are APA-K, AVI-D, SGTS, and C-terminally | ? | - |
? | |
complement factor C3b + H2O | Streptococcus pyogenes | cleavage sites are RTL-D, NHK-L, LAR-S, and VEL-I | ? | - |
? | |
decorin + H2O | Streptococcus pyogenes | - |
? | - |
? | |
EndoS + H2O | Streptococcus pyogenes | cleavage site is VML-K | ? | - |
? | |
Fba protein + H2O | Streptococcus pyogenes | - |
? | - |
? | |
Fibrinogen + H2O | Streptococcus pyogenes | cleavage sites are C-terminally in Aalpha chains | ? | - |
? | |
Fibronectin + H2O | Streptococcus pyogenes | - |
? | - |
? | |
H-kininogen + H2O | Streptococcus pyogenes | cleavage sites are LMK-R and PFR-S | ? | - |
? | |
human CXCL10 + H2O | Streptococcus pyogenes | - |
? | - |
? | |
immunoglobulin A + H2O | Streptococcus pyogenes | cleavage sites are the heavy chains | ? | - |
? | |
immunoglobulin D + H2O | Streptococcus pyogenes | cleavage sites are the heavy chains | ? | - |
? | |
immunoglobulin E + H2O | Streptococcus pyogenes | cleavage sites are the heavy chains | ? | - |
? | |
immunoglobulin G + H2O | Streptococcus pyogenes | cleavage site is LLG-G in gamma-chain | ? | - |
? | |
immunoglobulin M + H2O | Streptococcus pyogenes | cleavage sites are the heavy chains | ? | - |
? | |
Laminin + H2O | Streptococcus pyogenes | - |
? | - |
? | |
M protein + H2O | Streptococcus pyogenes | - |
? | - |
? | |
additional information | Streptococcus pyogenes | CXCL9 is quite resistant to hydrolysis by SpeB | ? | - |
? | |
plasminogen + H2O | Streptococcus pyogenes | - |
? | - |
? | |
pro-interleukin-1beta + H2O | Streptococcus pyogenes | cleavage site is YVH-D | interleukin-1beta + ? | - |
? | |
properdin + H2O | Streptococcus pyogenes | - |
? | - |
? | |
protein F1 + H2O | Streptococcus pyogenes | - |
? | - |
? | |
protein H + H2O | Streptococcus pyogenes | - |
? | - |
? | |
Sda1 + H2O | Streptococcus pyogenes | - |
? | - |
? | |
Slr + H2O | Streptococcus pyogenes | - |
? | - |
? | |
SmeZ + H2O | Streptococcus pyogenes | - |
? | - |
? | |
SpeBz + H2O | Streptococcus pyogenes | auto-cleavage sites are AIK-A, KVN-L, QIK-E, TYA-G, and EIK-Q | mature SpeB + ? | - |
? | |
streptokinase + H2O | Streptococcus pyogenes | - |
? | - |
? | |
streptolysin O + H2O | Streptococcus pyogenes | - |
? | - |
? | |
urokinase receptor + H2O | Streptococcus pyogenes | cleavage site is close to the GPI anchor | ? | - |
? | |
Vitronectin + H2O | Streptococcus pyogenes | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pyogenes | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha1-antitrypsin + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
C5a peptidase + H2O | cleavage sites are APA-K, AVI-D, SGTS, and C-terminally | Streptococcus pyogenes | ? | - |
? | |
complement factor C3b + H2O | cleavage sites are RTL-D, NHK-L, LAR-S, and VEL-I | Streptococcus pyogenes | ? | - |
? | |
decorin + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
EndoS + H2O | cleavage site is VML-K | Streptococcus pyogenes | ? | - |
? | |
Fba protein + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
Fibrinogen + H2O | cleavage sites are C-terminally in Aalpha chains | Streptococcus pyogenes | ? | - |
? | |
Fibronectin + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
H-kininogen + H2O | cleavage sites are LMK-R and PFR-S | Streptococcus pyogenes | ? | - |
? | |
human CXCL10 + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
immunoglobulin A + H2O | cleavage sites are the heavy chains | Streptococcus pyogenes | ? | - |
? | |
immunoglobulin D + H2O | cleavage sites are the heavy chains | Streptococcus pyogenes | ? | - |
? | |
immunoglobulin E + H2O | cleavage sites are the heavy chains | Streptococcus pyogenes | ? | - |
? | |
immunoglobulin G + H2O | cleavage site is LLG-G in gamma-chain | Streptococcus pyogenes | ? | - |
? | |
immunoglobulin M + H2O | cleavage sites are the heavy chains | Streptococcus pyogenes | ? | - |
? | |
Laminin + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
M protein + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
additional information | CXCL9 is quite resistant to hydrolysis by SpeB | Streptococcus pyogenes | ? | - |
? | |
plasminogen + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
pro-interleukin-1beta + H2O | cleavage site is YVH-D | Streptococcus pyogenes | interleukin-1beta + ? | - |
? | |
properdin + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
protein F1 + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
protein H + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
Sda1 + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
Slr + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
SmeZ + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
SpeBz + H2O | auto-cleavage sites are AIK-A, KVN-L, QIK-E, TYA-G, and EIK-Q | Streptococcus pyogenes | mature SpeB + ? | - |
? | |
streptokinase + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
streptolysin O + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
urokinase receptor + H2O | cleavage site is close to the GPI anchor | Streptococcus pyogenes | ? | - |
? | |
Vitronectin + H2O | - |
Streptococcus pyogenes | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 28000, mature enzyme | Streptococcus pyogenes |
? | x * 40000, proenzyme, estimated from amino acid sequence | Streptococcus pyogenes |
Synonyms | Comment | Organism |
---|---|---|
SpeB | - |
Streptococcus pyogenes |