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Literature summary for 3.4.22.10 extracted from

  • Wei, L.; Pandiripally, V.; Gregory, E.; Clymer, M.; Cue, D.
    Impact of the SpeB protease on binding of the complement regulatory proteins factor H and factor H-like protein 1 by Streptococcus pyogenes (2005), Infect. Immun., 73, 2040-2050.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.10

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Streptococcus pyogenes
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fba + H2O Streptococcus pyogenes a cell surface factor H- and factor H-like protein 1-binding protein of epithelial human cells, the enzyme inhibits complement regulatory protein factor H- and factor H-like protein 1 binding by proteolysis of the Fba protein, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fba + H2O a cell surface factor H- and factor H-like protein 1-binding protein of epithelial human cells, the enzyme inhibits complement regulatory protein factor H- and factor H-like protein 1 binding by proteolysis of the Fba protein, overview Streptococcus pyogenes ?
-
 ?
Fba + H2O a cell surface factor H- and factor H-like protein 1-binding protein of epithelial human cells Streptococcus pyogenes ?
-
 ?

Synonyms

Synonyms Comment Organism
SPE B protease
-
 Streptococcus pyogenes

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Streptococcus pyogenes

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
 assay at Streptococcus pyogenes