Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CA-074-OMe | blocks cysteine cathepsins in addition to CatB in in primary human antigen-presenting cells | Homo sapiens | |
Z-Arg-Leu-Arg-alpha-aza-glycyl-Ile-Val-OMe | i.e. ZRLR, a highly selective cathepsin B inhibitor, cell-permeable, almost complete inhibition at 0.0001 mM | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
B-lymphocyte | primary | Homo sapiens | - |
dendritic cell | primary | Homo sapiens | - |
mononuclear cell | from peripheral blood | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-benzyloxycarbonyl-Arg-Arg-4-methyl-7-amidocoumarin + H2O | - |
Homo sapiens | N-benzyloxycarbonyl-Arg-Arg + 4-methyl-7-aminocoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CatB | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
assay at room temperature | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
assay at | Homo sapiens |