Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | serum-starvation increases cathepsin B-like activation in zebrafish follicles, not due to an increase in gene expression. No effects on cathepsin B activity by human chorionic gonadotropin and 17beta-estradiol | Danio rerio |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CA-074-Me | - |
Danio rerio | |
additional information | No effects on cathepsin B activity by human chorionic gonadotropin and 17beta-estradiol | Danio rerio |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Danio rerio | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | Q6PH75 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
vitelline gland | - |
Danio rerio | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-benzyloxycarbonyl-Arg-Arg-4-methyl-7-amidocoumarin + H2O | - |
Danio rerio | N-benzyloxycarbonyl-Arg-Arg + 4-methyl-7-aminocoumarin | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
28 | - |
assay at | Danio rerio |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
assay at | Danio rerio |
General Information | Comment | Organism |
---|---|---|
physiological function | cathepsin B is involved in the regulation of apoptosis during serum-starvation in teleost follicles. Cathepsin B may play a role in the activation of the executioner caspase-3 | Danio rerio |