Application | Comment | Organism |
---|---|---|
drug development | cathepsin B is a target for development of inhibitors to lower amyloid-beta protein in Alzheimer's disease | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of cathepsin B deficient mice. Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein. No phenotypes, overview | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
C57BL/6 mice | - |
Mus musculus C57BL/6 | - |
C57BL/6 mice | - |
Synonyms | Comment | Organism |
---|---|---|
CatB | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein | Mus musculus |