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Literature summary for 3.4.22.1 extracted from

  • Hasan, L.; Mazzucchelli, L.; Liebi, M.; Lis, M.; Hunger, R.E.; Tester, A.; Overall, C.M.; Wolf, M.
    Function of liver activation-regulated chemokine/CC chemokine ligand 20 is differently affected by cathepsin B and cathepsin D processing (2006), J. Immunol., 176, 6512-6522.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
CA-074 0.001 mM Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-
membrane
-
Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
melanoma cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chemokine (C-C motif) ligand 20 + H2O CCL20 is also known as liver- and activation-regulated chemokine (LARC), MIP-3alpha, or exodus-1 Homo sapiens CCL20 1-66 isoform + ? cathepsin B specifically cleaves off four C-terminally located amino acids and generates a CCL20 1-66 isoform with full functional activity ?

Synonyms

Synonyms Comment Organism
Cath-B
-
Homo sapiens