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Literature summary for 3.4.22.1 extracted from

  • Wilson, L.R.; Good, R.T.; Panaccio, M.; Wijffels, G.L.; Sandeman, R.M.; Spithill, T.W.
    Fasciola hepatica: characterization and cloning of the major cathepsin B protease secreted by newly excysted juvenile liver fluke (1998), Exp. Parasitol., 88, 85-94.
    View publication on PubMed
Search for more literature for 3.4.22.1

Cloned(Commentary)

Cloned (Comment) Organism
-
 Fasciola hepatica

Inhibitors

Inhibitors Comment Organism Structure
L-3-carboxy-2,3-trans-epoxypropionyl-leucylamido-(4-guanidino)butane E-64 Fasciola hepatica

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Fasciola hepatica
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28790
-
 derived from cDNA sequence Fasciola hepatica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Proteins + H2O Fasciola hepatica
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Fasciola hepatica
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Arg-4-methylcoumarin 7-amide + H2O
-
 Fasciola hepatica benzyloxycarbonyl-Arg + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide + H2O
-
 Fasciola hepatica benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin-7-amide
-
 Fasciola hepatica benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?
Bovine serum albumin + H2O
-
 Fasciola hepatica Hydrolyzed bovine serum albumin
-
 ?
Proteins + H2O
-
 Fasciola hepatica ?
-
 ?
sheep immunoglobulin heavy chain + H2O
-
 Fasciola hepatica hydrolyzed sheep immunoglobulin heavy chain
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Fasciola hepatica