Literature summary for 3.4.21.B45 extracted from

Angelopoulou, K.; Prassas, I.; Yousef, G.M.
The canine kallikrein-related peptidase 14: structural characterization, alternative splicing and differential expression in mammary cancer (2009), Gene, 446, 68-74.

Search for more literature for 3.4.21.B45

Protein Variants

Protein Variants	Comment	Organism
I155N	natural polymorphism	Canis lupus familiaris

Organism

Organism	UniProt	Comment	Textmining
Canis lupus familiaris	C7T1J3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	the classical form of KLK14 and splice variant 3 are almost ubiquitously expressed in both normal and neoplastic tissues. Splice variant 1 is predominantly detected in normal tissues. The classical form and splice variants 1 and 2 exhibit lower expression levels in tumor compared to normal tissues. All encoded protein products of the splice variants are predicted to be truncated and catalytically inactive	Canis lupus familiaris	-

Expression

Organism	Comment	Expression
Canis lupus familiaris	in addition to the classical form of the gene, five splice variants were identified. The splicing events involve 5'-truncation or complete elimination of exon 4 and/or retention of intron I. All encoded protein products of the splice variants are predicted to be truncated and catalytically inactive	additional information

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Release 2023.1 (January 2023)