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Literature summary for 3.4.21.B42 extracted from

  • Sano, A.; Sangai, T.; Maeda, H.; Nakamura, M.; Hasebe, T.; Ochiai, A.
    Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3 (2007), Int. J. Oncol., 30, 1493-1498.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Phenylmethylsulfonylfluoride 20 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UBX7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast carcinoma cell
-
Homo sapiens
-
mammary gland
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-
MDA-MB-231 cell
-
Homo sapiens
-
MDA-MB-468 cell
-
Homo sapiens
-
T-47D cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin-like growth factor-binding protein 3 + H2O insulin-like growth factor-binding protein 3 is cleaved into 3 fragments of 25000, 20000 and 17000 Da length, respectively Homo sapiens ?
-
?
additional information kallikrein 11 is able to degrade itself Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
kallikrein 11
-
Homo sapiens