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Literature summary for 3.4.21.B26 extracted from

  • Okada, H.; Nie, G.; Salamonsen, L.A.
    Requirement for proprotein convertase 5/6 during decidualization of human endometrial stromal cells in vitro (2005), J. Clin. Endocrinol. Metab., 90, 1028-1034.
    View publication on PubMed
Search for more literature for 3.4.21.B26

Activating Compound

Activating Compound Comment Organism Structure
additional information significant increase in PC5/6 mRNA levels in endometrial stromal cells treated with 17beta-estradiol plus medroxyprogesterone acetate during decidualization, whereas 17beta-estradiol alone has no effect Homo sapiens

Application

Application Comment Organism
medicine PC5/6 plays a key role for decidualization in human endometrium and its action is necessary for prolactin production from endometrial stromal cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
65000
-
 Western blot analysis, C-terminally truncated form in decidualized endometrial stromal cells Homo sapiens
117000
-
 Western blot analysis, mature form in decidualized endometrial stromal cells Homo sapiens
126000
-
 Western blot analysis, proform in decidualized endometrial stromal cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q92824
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
endometrial cell line decidualized and undecidualized cells Homo sapiens
-
stromal cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
PC5/6
-
 Homo sapiens