Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.B12 extracted from

  • Debela, M.; Magdolen, V.; Schechter, N.; Valachova, M.; Lottspeich, F.; Craik, C.S.; Choe, Y.; Bode, W.; Goettig, P.
    Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences (2006), J. Biol. Chem., 281, 25678-25688.
    View publication on PubMed
Search for more literature for 3.4.21.B12

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli M15(pREP4) cells and in insect cells (nur hk5) Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9Y5K2 precursor
-

Purification (Commentary)

Purification (Comment) Organism
nickel-nitrilotriacetic acid-Sepharose column chromatography and benzamidine-Sepharose column chromatography Homo sapiens

Renatured (Commentary)

Renatured (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
prostate gland
-
 Homo sapiens
-
tooth
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-FR-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-FR + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-LR-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-LR + 7-amino-4-methylcoumarin
-
 ?
additional information clearly prefers P1-Arg over Lys and Tyr Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
enamel matrix serine protease 1
-
 Homo sapiens
HK4 displays a trypsin-like specificity with strong preference for P1-Arg Homo sapiens
KLK-L1
-
 Homo sapiens
prostase
-
 Homo sapiens