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Literature summary for 3.4.21.98 extracted from

  • Lenz, O.; Verbinnen, T.; Lin, T.I.; Vijgen, L.; Cummings, M.D.; Lindberg, J.; Berke, J.M.; Dehertogh, P.; Fransen, E.; Scholliers, A.; Vermeiren, K.; Ivens, T.; Raboisson, P.; Edlund, M.; Storm, S.; Vrang, L.; de Kock, H.; Fanning, G.C.; Simmen, K.A.
    In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435 (2010), Antimicrob. Agents Chemother., 54, 1878-1887.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
BILN2061
-
Hepacivirus C
boceprevir
-
Hepacivirus C
ITMN-191
-
Hepacivirus C
telaprevir
-
Hepacivirus C
TMC435 small-molecule reversible noncovalent inhibitor of the NS3/4A serine protease Hepacivirus C

Organism

Organism UniProt Comment Textmining
Hepacivirus C
-
-
-

Synonyms

Synonyms Comment Organism
NS3
-
Hepacivirus C
NS3 protease
-
Hepacivirus C