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Literature summary for 3.4.21.97 extracted from

  • Bonneau, P.R.; Grand-Maitre, C.; Greenwood, D.J.; Lagac, L.; LaPlante, S.R.; Massariol., M.J.; Ogilvie, W.W.; OæMeara, J.A.; Kawai, S.H.
    Evidence of a conformational change in the human cytomegalovirus protease upon binding of peptidyl-activated carbonyl inhibitors (1997), Biochemistry, 36, 12644-12652.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-[2-(3,3-Dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-N1-(1-methyl-2-oxo-propyl)-succinamide
-
Human betaherpesvirus 5
2-[2-(3,3-Dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-N1-(3,3,3-trifluoro-1-methyl-2-oxo-propyl)-succinamide
-
Human betaherpesvirus 5
2-[2-(3,3-Dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-N1-(3,3,4,4,4-pentafluoro-1-methyl-2-oxo-butyl)-succinamide
-
Human betaherpesvirus 5
Ac-Gly-Val-Val-Asn-Ala chloromethyl ketone
-
Human betaherpesvirus 5
N1-(2-Benzylcarbamoyl-1-methyl-2-oxo-ethyl)-2-[2-(3,3-dimethyl-butanoylamino)-3,3-dimethyl-butanoylamino]-N4,N4-dimethyl-succinamide
-
Human betaherpesvirus 5

Organism

Organism UniProt Comment Textmining
Human betaherpesvirus 5
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Abz-VVNASSLY(3-NO2)R-OH + H2O
-
Human betaherpesvirus 5 Abz-VVNA + SSLY(3-NO2)R-OH
-
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