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Literature summary for 3.4.21.97 extracted from
- Investigation of the induced-fit mechanism and catalytic activity of the human cytomegalovirus protease homodimer via molecular dynamics simulations (2003), Proteins Struct. Funct. Genet., 52, 483-491.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human betaherpesvirus 5 | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| Cleaves -Ala-/-Ser- and -Ala-/-Ala- bonds in the scaffold protein | serine protease that operates by an induced-fit mechanism | Human betaherpesvirus 5 |
aSubunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | dimeric form is necessary to activate the enzyme because of an induced stabilization of the oxyanion hole | Human betaherpesvirus 5 |
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